Organocatalysis and New Strategies

OrganoCatalysis refers to catalysis, whereby the rate of a chemical reaction can increase by an organic catalyst referred to as an catalyst that consists of carbon, hydrogen, sulfur and other non metal elements found in organic compounds.Organocatalysts which display secondary amine functionality is described as performing either double bond catalysis by forming catalytic quantities of an active double bond nucleophile or imminium catalysis by forming catalytic quantities of an activated imminium electron acceptor . This mechanism is typical for covalent organocatalysis. The advantages of these catalyst include their lack of sensitivity to moisture and oxygen, their ready availability, low price, and low toxicity, which confers a huge direct benefit in the yield of pharmaceutical intermediates when compared with (transition) metal catalysts.